Arrowsmith - Sinclair Lewis (books suggested by bill gates .txt) 📗

which dissolves the staphylococci from the pus in question.”

When he had finished, at seven, his head was on his notebook and he was asleep.

He awoke at ten, went home, ate like a savage, slept again, and was in the laboratory before dawn. His next rest was an hour that afternoon, sprawled on his laboratory table, with his garçon on guard; the next, a day and a half later, was eight hours in bed, from dawn till noon.

But in dreams he was constantly upsetting a rack of test-tubes or breaking a flask. He discovered an X Principle which dissolved chairs, tables, human beings. He went about smearing it on Bert Tozers and Dr. Bissexes and fiendishly watching them vanish, but accidentally he dropped it on Leora and saw her fading, and he woke screaming to find the real Leora’s arms about him, while he sobbed, “Oh, I couldn’t do anything without you! Don’t ever leave me! I do love you so, even if this damned work does keep me tied up. Stay with me!”

While she sat by him on the frowsy bed, gay in her gingham, he went to sleep, to wake up three hours later and start off for the Institute, his eyes blood-glaring and set. She was ready for him with strong coffee, waiting on him silently, looking at him proudly, while he waved his arms, babbling:

“Gottlieb better not talk any more about the importance of new observations! The X Principle may not just apply to staph. Maybe you can sic it on any bug⁠—cure any germ disease by it. Bug that lives on bugs! Or maybe it’s a chemical principle, an enzyme. Oh, I don’t know. But I will!”

As he bustled to the Institute he swelled with the certainty that after years of stumbling he had arrived. He had visions of his name in journals and textbooks; of scientific meetings cheering him. He had been an unknown among the experts of the Institute, and now he pitied all of them. But when he was back at his bench the grandiose aspirations faded and he was the sniffing, snuffling beagle, the impersonal worker. Before him, supreme joy of the investigator, new mountain-passes of work opened, and in him was new power.

II

For a week Martin’s life had all the regularity of an escaped soldier in the enemy’s country, with the same agitation and the same desire to prowl at night. He was always sterilizing flasks, preparing media of various hydrogen-ion concentrations, copying his old notes into a new book lovingly labeled “X Principle, Staph,” and adding to it further observations. He tried, elaborately, with many flasks and many reseedings, to determine whether the X Principle would perpetuate itself indefinitely, whether when it was transmitted from tube to new tube of bacteria it would reappear, whether, growing by cell-division automatically, it was veritably a germ, a sub-germ infecting germs.

During the week Gottlieb occasionally peered over his shoulder, but Martin was unwilling to report until he should have proof, and one good night’s sleep, and perhaps even a shave.

When he was sure that the X Principle did reproduce itself indefinitely, so that in the tenth tube it grew to have as much effect as in the first, then he solemnly called on Gottlieb and laid before him his results, with his plans for further investigation.

The old man tapped his thin fingers on the report, read it intently, looked up and, not wasting time in congratulations, vomited questions:

Have you done dis? Why have you not done dat? At what temperature is the activity of the Principle at its maximum? Is its activity manifested on agar-solid medium?

“This is my plan for new work. I think you’ll find it includes most of your suggestions.”

“Huh!” Gottlieb ran through it and snorted, “Why have you not planned to propagate it on dead staph? That is most important of all.”

“Why?”

Gottlieb flew instantly to the heart of the jungle in which Martin had struggled for many days: “Because that will show whether you are dealing with a living virus.”

Martin was humbled, but Gottlieb beamed:

“You haf a big thing. Now do not let the Director know about this and get enthusiastic too soon. I am glad, Martin!”

There was that in his voice which sent Martin swanking down the corridor, back to work⁠—and to not sleeping.

What the X Principle was⁠—chemical or germ⁠—he could not determine, but certainly the original Principle flourished. It could be transmitted indefinitely; he determined the best temperature for it and found that it did not propagate on dead staphylococcus. When he added a drop containing the Principle to a growth of staphylococcus which was a gray film on the solid surface of agar, the drop was beautifully outlined by bare patches, as the enemy made its attack, so that the agar slant looked like moth-eaten beeswax. But within a fortnight one of the knots of which Gottlieb warned him appeared.

Wary of the hundreds of bacteriologists who would rise to slay him once his paper appeared, he sought to make sure that his results could be confirmed. At the hospital he obtained pus from many boils, of the arms, the legs, the back; he sought to reduplicate his results⁠—and failed, complete. No X Principle appeared in any of the new boils, and sadly he went to Gottlieb.

The old man meditated, asked a question or two, sat hunched in his cushioned chair, and demanded:

“What kind of a carbuncle was the original one?”

“Gluteal.”

“Ah, den the X Principle may be present in the intestinal contents. Look for it, in people with boils and without.”

Martin dashed off. In a week he had obtained the Principle from intestinal contents and from other gluteal boils, finding an especial amount in boils which were “healing of themselves”; and he transplanted his new Principle, in a heaven of triumph, of admiration for Gottlieb. He extended his investigation to the intestinal group of organisms and discovered an X Principle against the colon bacillus. At the same time he gave some of the original Principle