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and mechanical injuries farther out than radiation effects.

Medical findings show that no person was injured by radioactivity who was not exposed to the actual explosion of the bombs. No injuries resulted from persistent radioactivity of any sort.

BURNS

Two types of burns were observed. These are generally differentiated as flame or fire burn and so-called flash burn.

The early appearance of the flame burn as reported by the Japanese, and the later appearance as observed, was not unusual.

The flash burn presented several distinctive features. Marked redness of the affected skin areas appeared almost immediately, according to the Japanese, with progressive changes in the skin taking place over a period of a few hours. When seen after 50 days, the most distinctive feature of these burns was their sharp limitation to exposed skin areas facing the center of the explosion. For instance, a patient who had been walking in a direction at right angles to a line drawn between him and the explosion, and whose arms were swinging, might have burns only on the outside of the arm nearest the center and on the inside of the other arm.

Generally, any type of shielding protected the skin against flash burns, although burns through one, and very occasionally more, layers of clothing did occur in patients near the center. In such cases, it was not unusual to find burns through black but not through white clothing, on the same patient. Flash burns also tended to involve areas where the clothes were tightly drawn over the skin, such as at the elbows and shoulders.

The Japanese report the incidence of burns in patients surviving more than a few hours after the explosion, and seeking medical attention, as high as 95%. The total mortalities due to burns alone cannot be estimated with any degree of accuracy. As mentioned already, it is believed that the majority of all the deaths occurred immediately. Of these, the Japanese estimate that 75%, and most of the reports estimate that over 50%, of the deaths were due to burns.

In general, the incidence of burns was in direct proportion to the distance from X. However, certain irregularities in this relationship result in the medical studies because of variations in the amount of shielding from flash burn, and because of the lack of complete data on persons killed outright close to X.

The maximum distance from X at which flash burns were observed is of paramount interest. It has been estimated that patients with burns at Hiroshima were all less than 7,500 feet from the center of the explosion at the time of the bombing. At Nagasaki, patients with burns were observed out to the remarkable distance of 13,800 feet.

MECHANICAL INJURIES

The mechanical injuries included fractures, lacerations, contusions, abrasions, and other effects to be expected from falling roofs, crumbling walls, flying debris and glass, and other indirect blast effects. The appearance of these various types of mechanical injuries was not remarkable to the medical authorities who studied them.

It was estimated that patients with lacerations at Hiroshima were less than 10,600 feet from X, whereas at Nagasaki they extended as far as 12,200 feet.

The tremendous drag of wind, even as far as 1 mile from X, must have resulted in many injuries and deaths. Some large pieces of a prison wall, for example, were flung 80 feet, and many have gone 30 feet high before falling. The same fate must have befallen many persons, and the chances of a human being surviving such treatment are probably small.

BLAST INJURIES

No estimate of the number of deaths or early symptoms due to blast pressure can be made. The pressures developed on the ground under the explosions were not sufficient to kill more than those people very near the center of damage (within a few hundred feet at most). Very few cases of ruptured ear drums were noted, and it is the general feeling of the medical authorities that the direct blast effects were not great. Many of the Japanese reports, which are believed to be false, describe immediate effects such as ruptured abdomens with protruding intestines and protruding eyes, but no such results were actually traced to the effect of air pressure alone.

RADIATION INJURIES

As pointed out in another section of this report the radiations from the nuclear explosions which caused injuries to persons were primarily those experienced within the first second after the explosion; a few may have occurred later, but all occurred in the first minute. The other two general types of radiation, viz., radiation from scattered fission products and induced radioactivity from objects near the center of explosion, were definitely proved not to have caused any casualties.

The proper designation of radiation injuries is somewhat difficult. Probably the two most direct designations are radiation injury and gamma ray injury. The former term is not entirely suitable in that it does not define the type of radiation as ionizing and allows possible confusion with other types of radiation (e.g., infra-red). The objection to the latter term is that it limits the ionizing radiation to gamma rays, which were undoubtedly the most important; but the possible contribution of neutron and even beta rays to the biological effects cannot be entirely ignored. Radiation injury has the advantage of custom, since it is generally understood in medicine to refer to X-ray effect as distinguished from the effects of actinic radiation. Accordingly, radiation injury is used in this report to mean injury due only to ionizing radiation.

According to Japanese observations, the early symptons in patients suffering from radiation injury closely resembled the symptons observed in patients receiving intensive roentgen therapy, as well as those observed in experimental animals receiving large doses of X-rays. The important symptoms reported by the Japanese and observed by American authorities were epilation (lose of hair), petechiae (bleeding into the skin), and other hemorrhagic manifestations, oropharyngeal lesions (inflammation of the mouth and throat), vomiting, diarrhea, and fever.

Epilation was one of the most spectacular and obvious findings. The appearance of the epilated patient was typical. The crown was involved more than the sides, and in many instances the resemblance to a monk's tonsure was striking. In extreme cases the hair was totally lost. In some cases, re-growth of hair had begun by the time patients were seen 50 days after the bombing. Curiously, epilation of hair other than that of the scalp was extremely unusual.

Petechiae and other hemorrhagic manifestations were striking findings. Bleeding began usually from the gums and in the more seriously affected was soon evident from every possible source. Petechiae appeared on the limbs and on pressure points. Large ecchymoses (hemorrhages under the skin) developed about needle punctures, and wounds partially healed broke down and bled freely. Retinal hemorrhages occurred in many of the patients. The bleeding time and the coagulation time were prolonged. The platelets (coagulation of the blood) were characteristically reduced in numbers.

Nausea and vomiting appearing within a few hours after the explosion was reported frequently by the Japanese. This usually had subsided by the following morning, although occasionally it continued for two or three days. Vomiting was not infrequently reported and observed during the course of the later symptoms, although at these times it generally appeared to be related to other manifestation of systemic reactions associated with infection.

Diarrhea of varying degrees of severity was reported and observed. In the more severe cases, it was frequently bloody. For reasons which are not yet clear, the diarrhea in some cases was very persistent.

Lesions of the gums, and the oral mucous membrane, and the throat were observed. The affected areas became deep red, then violacious in color; and in many instances ulcerations and necrosis (breakdown of tissue) followed. Blood counts done and recorded by the Japanese, as well as counts done by the Manhattan Engineer District Group, on such patients regularly showed leucopenia (low-white blood cell count). In extreme cases the white blood cell count was below 1,000 (normal count is around 7,000). In association with the leucopenia and the oropharyngeal lesions, a variety of other infective processes were seen. Wounds and burns which were healing adequately suppurated and serious necrosis occurred. At the same time, similar ulcerations were observed in the larynx, bowels, and in females, the gentalia. Fever usually accompanied these lesions.

Eye injuries produced by the atomic bombings in both cities were the subject of special investigations. The usual types of mechanical injuries were seen. In addition, lesions consisting of retinal hemorrhage and exudation were observed and 75% of the patients showing them had other signs of radiation injury.

The progress of radiation disease of various degrees of severity is shown in the following table:

  Summary of Radiation Injury
  Clinical Symptoms and Findings

  Day
  after
  Explo-
  sion Most Severe Moderately Severe Mild
    1. 1. Nausea and vomiting 1. Nausea and vomiting
    2. after 1-2 hours. after 1-2 hours.
    3. NO DEFINITE SYMPTOMS
    4.
    5. 2. Diarrhea
    6. 3. Vomiting NO DEFINITE SYMPTOMS
    7. 4. Inflammation of the
             mouth and throat
    8. 5. Fever
    9. 6. Rapid emaciation
   10. Death NO DEFINITE SYMPTOMS
   11. (Mortality probably 2. Beginning epilation.
   12. 100%)
   13.
   14.
   15.
   16.
   17.
   18. 3. Loss of appetite
   19. and general malaise. 1. Epilation
   20. 4. Fever. 2. Loss of appetite
   21. 5. Severe inflammation and malaise.
   22. of the mouth and throat 3. Sore throat.
   23. 4. Pallor.
   24. 5. Petechiae
   25. 6. Diarrhea
   26. 7. Moderate emacia-
   27.

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